Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ASIC1 | P78348 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4681613 | 1.00 | MAPT (0.40) | MAPTKDM4EASIC1POLBALDH1A1 | |
| SCHEMBL4685195 | 0.87 | ASIC1 (0.47) | MAPTKDM4EASIC1ALDH1A1NPC1 | |
| SCHEMBL4685196 | 0.87 | ASIC1 (0.47) | MAPTKDM4EASIC1ALDH1A1NPC1 | |
| SCHEMBL4679239 | 0.80 | KDM4E (0.38) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL5411282 | 0.80 | KDM4E (0.38) | MAPTKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL4744870 | 0.80 | TOP1 (0.39) | MAPTASIC1ALDH1A1NPC1RAB9A | |
| SCHEMBL14445915 | 0.80 | TOP1 (0.39) | MAPTASIC1ALDH1A1NPC1RAB9A | |
| SCHEMBL4679253 | 0.76 | RAB9A (0.36) | MAPTASIC1ALDH1A1NPC1RAB9A | |
| SCHEMBL4679257 | 0.76 | RAB9A (0.36) | MAPTASIC1ALDH1A1NPC1RAB9A | |
| SCHEMBL20871240 | 0.73 | S100B (0.64) | MAPTKDM4EPOLBALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |