Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679560 | 1.00 | OPRM1 (0.55) | OPRM1OPRK1OPRL1ALDH1A1TSHR | |
| SCHEMBL4737483 | 0.96 | OPRM1 (0.53) | OPRM1OPRK1OPRL1ALDH1A1TSHR | |
| SCHEMBL27782364 | 0.83 | OPRM1 (0.58) | OPRM1OPRK1OPRL1ALDH1A1TSHR | |
| SCHEMBL27804049 | 0.80 | ALDH1A1 (0.58) | OPRM1OPRK1OPRL1ALDH1A1KDM4E | |
| SCHEMBL7682877 | 0.80 | OPRM1 (0.57) | OPRM1OPRK1OPRL1ALDH1A1TSHR | |
| SCHEMBL4680510 | 0.80 | OPRM1 (0.66) | OPRM1OPRK1OPRL1 | |
| SCHEMBL3636451 | 0.80 | OPRM1 (0.72) | OPRM1OPRK1OPRL1ALDH1A1TSHR | |
| SCHEMBL3751742 | 0.78 | CHRM2 (0.60) | OPRM1OPRK1OPRL1ALDH1A1TSHR | |
| SCHEMBL3751747 | 0.78 | CHRM2 (0.60) | OPRM1OPRK1OPRL1ALDH1A1TSHR | |
| SCHEMBL1837269 | 0.78 | OPRM1 (0.54) | OPRM1OPRK1OPRL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |