Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 7/20 | 0.41 |
| ▸ | PRKCB | P05771 | 6/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.41 |
| ▸ | PRKCH | P24723 | 4/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 6/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RGS12 | O14924 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2950533 | 0.84 | PRKCA (0.59) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL2955891 | 0.77 | PRKCA (0.59) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL13166896 | 0.74 | PRKCA (0.65) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL4740368 | 0.74 | PRKCA (0.67) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL4680242 | 0.71 | PRKCA (0.72) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL2954303 | 0.71 | PRKCA (0.59) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL2945607 | 0.70 | PRKCA (0.81) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL4680012 | 0.69 | PRKCA (0.61) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL4675316 | 0.68 | PRKCA (0.56) | PRKCAPRKCBPRKCDPRKCHPRKCQ | |
| SCHEMBL4676611 | 0.68 | PRKCA (0.65) | PRKCAPRKCBPRKCDPRKCHPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |