Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 8/20 | 0.72 |
| ▸ | PRKCB | P05771 | 7/20 | 0.72 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.72 |
| ▸ | PRKCH | P24723 | 3/20 | 0.72 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.72 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.72 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 5/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 3/20 | 0.56 |
| ▸ | PRKACG | P22612 | 3/20 | 0.56 |
| ▸ | PRKACB | P22694 | 3/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 4/20 | 0.52 |
| ▸ | CDK1 | P06493 | 4/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740368 | 0.95 | PRKCA (0.67) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL2945607 | 0.95 | PRKCA (0.81) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL4680012 | 0.91 | PRKCA (0.61) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL2955891 | 0.89 | PRKCA (0.59) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL2954303 | 0.88 | PRKCA (0.59) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL2950533 | 0.88 | PRKCA (0.59) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL6192685 | 0.87 | CAMK2D (0.57) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL4675316 | 0.86 | PRKCA (0.56) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL4676201 | 0.86 | CAMK2D (0.65) | PRKCAPRKCBPRKCEPRKCHPRKCQ | |
| SCHEMBL4676611 | 0.86 | PRKCA (0.65) | PRKCAPRKCBPRKCEPRKCHPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |