Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.51 |
| ▸ | PRKCA | P17252 | 9/20 | 0.49 |
| ▸ | PRKCB | P05771 | 2/20 | 0.48 |
| ▸ | PRKCG | P05129 | 1/20 | 0.48 |
| ▸ | PRKCH | P24723 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4676750 | 0.91 | GSK3B (0.50) | GSK3BPRKCAPRKCBPRKCGCAMK2D | |
| SCHEMBL2946233 | 0.85 | PRKCA (0.51) | GSK3BPRKCAPRKCBPRKCGPRKCH | |
| SCHEMBL4680124 | 0.81 | PRKCA (0.47) | GSK3BPRKCAPRKCBPRKCGPRKCH | |
| SCHEMBL7541680 | 0.78 | GSK3B (0.72) | GSK3BPRKCAGSK3A | |
| SCHEMBL7529358 | 0.78 | GSK3B (0.72) | GSK3BPRKCAGSK3A | |
| SCHEMBL5756702 | 0.75 | GSK3B (0.71) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL4684125 | 0.74 | PRKCA (0.62) | GSK3BPRKCAPRKCBPRKCGPRKCH | |
| SCHEMBL3775971 | 0.72 | GSK3B (0.61) | GSK3BPRKCAPRKCBPRKCGPRKCD | |
| SCHEMBL20387059 | 0.70 | GSK3B (0.66) | GSK3BPRKCAQPCTGSK3A | |
| SCHEMBL4683218 | 0.70 | GSK3B (0.55) | GSK3BPRKCAPRKCBPRKCHPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513520-B1 | SUBSTITUTED PYRROLINES AS KINASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-09-24 | — | — | EP | disclosed |