SCHEMBL468007

SCHEMBL468007

FC(F)(F)c1ccc(-c2nccc(Oc3ccccc3C(F)(F)F)n2)cc1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 1/20 0.42
ALOX5AP P20292 4/20 0.42
FEN1 P39748 4/20 0.42
TRPV3 Q8NET8 4/20 0.41
KMT2A Q03164 1/20 0.40
GRM5 P41594 1/20 0.39
HTR1A P08908 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6182443 0.82 FFAR4 (0.48) TRPV3KMT2AHPGD
SCHEMBL336755 0.76 FFAR4 (0.52) P2RY1KMT2A
SCHEMBL29387718 0.76 FFAR4 (0.52) P2RY1KMT2A
SCHEMBL6049402 0.74 ALOX5AP (0.42) ALOX5APFEN1TRPV3
SCHEMBL18469 0.73 CTSS (0.42) P2RY1ALOX5APFEN1HTR1ASLC6A2
SCHEMBL10495486 0.73 KMT2A (0.70) KMT2AHPGD
SCHEMBL5252670 0.73 S1PR1 (0.52) ALOX5APFEN1TRPV3
SCHEMBL10163847 0.72 TRPV3 (0.42) TRPV3
SCHEMBL6177990 0.72 FFAR4 (0.53) P2RY1KMT2A
SCHEMBL3601560 0.72 TTR (0.45) P2RY1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2385756-A1 SOYBEAN EVENT 127 AND METHODS RELATED THERETO BASF Agrochemical Products, B.V. (NL) 2011-11-16 EP disclosed
US-8041483-B2 Exterior airbag deployment techniques AUTOMOTIVE TECHNOLOGIES INTERNATIONAL, INC. (US) 2011-10-18 US disclosed