Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 4/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28527509 | 0.95 | TSHR (0.46) | TSHROR51E2CAMK2AGPR84FFAR1 | |
| Oxalic Acid SCHEMBL28524606 | 0.95 | TSHR (0.46) | TSHROR51E2CAMK2AGPR84FFAR1 | |
| Succinic Acid SCHEMBL28436442 | 0.84 | LMNA (0.64) | TSHROR51E2CAMK2AGPR84FFAR1 | |
| Malonic Acid SCHEMBL28435070 | 0.84 | LDHA (0.64) | TSHROR51E2CAMK2AGPR84FFAR1 | |
| Bicarbonate SCHEMBL9488228 | 0.84 | TSHR (0.56) | TSHROR51E2CAMK2AGPR84FFAR1 | |
| Bicarbonate SCHEMBL310739 | 0.84 | — | — | |
| Bicarbonate SCHEMBL28880335 | 0.84 | TSHR (0.56) | TSHROR51E2CAMK2AGPR84FFAR1 | |
| Oxalic Acid SCHEMBL29462937 | 0.82 | CAMK2A (0.53) | TSHROR51E2CAMK2AGPR84FFAR1 | |
| Bicarbonate SCHEMBL11775796 | 0.80 | TSHR (0.50) | TSHROR51E2CAMK2AGPR84FFAR1 | |
| Bicarbonate SCHEMBL19410354 | 0.80 | TSHR (0.50) | TSHROR51E2CAMK2AGPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751408-A | Preparation method of high-purity vinyl oxalate | 中国科学院宁波材料技术与工程研究所 | 2025-04-04 | — | — | CN | claimed |
| CN-115785416-B | Poly (ethylene glycol-co-diethylene glycol) oxalate and preparation method thereof | 新倍斯(杭州)材料科技有限公司 | 2024-01-19 | — | — | CN | claimed |
| CN-116836522-A | Seawater-degradable PBAT polyester composition, preparation method and application | 大连理工大学 | 2023-10-03 | — | — | CN | claimed |
| CN-107673974-B | Recycling method and device for nitrogen oxides | 上海华谊能源化工有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-115785406-B | Preparation method of kilogram-level polyethylene glycol oxalate | 新倍斯(杭州)材料科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-115569234-A | Basalt fiber pipe sleeve for prosthetic socket and preparation method thereof | 北京连续玄武岩纤维科技有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-115527436-A | Metal work card sprayed with acrylic paint information and cleaning method thereof | 深圳市中孚能电气设备有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-111576092-B | Method for manufacturing tipping paper for cigarettes with lasting normal sweetness | 江苏中烟工业有限责任公司 | 2022-05-24 | — | — | CN | claimed |
| CN-111519464-B | Sweetener composition for dry food packaging paper | 江苏中烟工业有限责任公司 | 2022-05-17 | — | — | CN | claimed |
| CN-113372542-A | Preparation method of bio-based polyethylene glycol oxalate resin | 俏东方生物燃料集团有限公司 | 2021-09-10 | — | — | CN | claimed |
| CN-111576092-A | Method for manufacturing tipping paper for cigarettes with lasting normal sweetness | 江苏中烟工业有限责任公司 | 2020-08-25 | — | — | CN | claimed |
| CN-111519464-A | Sweetener composition for dry food packaging paper | 江苏中烟工业有限责任公司 | 2020-08-11 | — | — | CN | claimed |
| CN-209619242-U | The recovery system of synthesis gas preparing ethylene glycol oxalate process byproduct methyl formate | PUYANG ZHIFENG CHEMICAL CO LTD | 2019-11-12 | — | — | CN | claimed |
| CN-207596755-U | A kind of recycling plant of nitrogen oxides | 上海华谊能源化工有限公司 | 2018-07-10 | — | — | CN | claimed |
| CN-107673974-A | The recycling method and device of a kind of nitrogen oxides | 上海华谊能源化工有限公司 | 2018-02-09 | — | — | CN | claimed |
| EP-2379059-A1 | CONTROLLED RELEASING COMPOSITION | Anhui Zhongren Technology Co., Ltd. (CN) | 2011-10-26 | — | — | EP | claimed |
| US-8041070-B2 | Speaker | HOSIDEN CORPORATION (JP) | 2011-10-18 | — | — | US | claimed |
| US-20110244043-A1 | Controlled releasing composition | XU JIANJIAN | 2011-10-06 | — | — | US | claimed |
| WO-2010066203-A1 | CONTROLLED RELEASING COMPOSITION | ANHUI ZHONGREN TECHNOLOGY CO., LTD. (CN) | 2010-06-17 | — | — | WO | claimed |
| EP-4038046-B1 | PROCESS FOR PREPARING DIALKYL CARBONATE AND ALKANEDIOL | SHELL INT RESEARCH (NL) | 2025-11-26 | — | — | EP | disclosed |
| WO-2025228928-A1 | PROCESS FOR THE PRODUCTION OF A HIGH MOLECULAR WEIGHT POLYESTER (CO)POLYMER | AVANTIUM KNOWLEDGE CENTRE B.V. (NL) | 2025-11-06 | — | — | WO | disclosed |
| EP-4612214-A1 | PROCESS FOR THE PRODUCTION OF A BIODEGRADABLE POLYESTER (CO)POLYMER | Avantium Knowledge Centre B.V. (NL) | 2025-09-10 | — | — | EP | disclosed |
| EP-4612215-A1 | PROCESS FOR THE PRODUCTION OF A HIGH MOLECULAR WEIGHT POLYESTER (CO)POLYMER | Avantium Knowledge Centre B.V. (NL) | 2025-09-10 | — | — | EP | disclosed |
| EP-4612235-A1 | PROCESS FOR THE PRODUCTION OF A HIGH MOLECULAR WEIGHT POLYESTER (CO)POLYMER | Avantium Knowledge Centre B.V. (NL) | 2025-09-10 | — | — | EP | disclosed |
| CN-120158070-A | Polycarbonate composition and preparation method and application thereof | 金发科技股份有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-119751408-A | Preparation method of high-purity vinyl oxalate | 中国科学院宁波材料技术与工程研究所 | 2025-04-04 | — | — | CN | disclosed |
| CN-119661818-A | Polyethylene-like degradable copolyester, and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2025-03-21 | — | — | CN | disclosed |
| CN-119350607-A | Preparation method of high molecular weight poly (alkyl oxalate) homopolymer and copolymer | 青岛科技大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-119285600-A | Preparation method of cyclic alkyl oxalate and ring-opening copolymerization thereof | 青岛科技大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-119019956-A | Adhesive, positive plate, negative plate, battery pack and electric equipment | 比亚迪股份有限公司 | 2024-11-26 | — | — | CN | disclosed |
| US-20240326393-A1 | MULTILAYER FILM, MULTILAYER BODY, PACKAGE AND PACKAGED ARTICLE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-10-03 | — | — | US | disclosed |
| US-12098125-B2 | Process for preparing dialkyl carbonate and alkanediol | SHELL USA, INC. (US) | 2024-09-24 | — | — | US | disclosed |
| CN-221182803-U | Esterification pre-reaction device for coal glycol | 鄂托克旗建元煤化科技有限责任公司 | 2024-06-21 | — | — | CN | disclosed |
| WO-2024094633-A1 | PROCESS FOR THE PRODUCTION OF A HIGH MOLECULAR WEIGHT POLYESTER (CO)POLYMER | AVANTIUM KNOWLEDGE CENTRE B.V. (NL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024094614-A1 | PROCESS FOR THE PRODUCTION OF A BIODEGRADABLE POLYESTER (CO)POLYMER | AVANTIUM KNOWLEDGE CENTRE B.V. (NL) | 2024-05-10 | — | — | WO | disclosed |
| WO-2024094621-A1 | PROCESS FOR THE PRODUCTION OF A HIGH MOLECULAR WEIGHT POLYESTER (CO)POLYMER | AVANTIUM KNOWLEDGE CENTRE B.V. (NL) | 2024-05-10 | — | — | WO | disclosed |
| CN-117844399-A | Cobalt salt adhesive and preparation method thereof | 江苏卡欧化工股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117683244-A | Method for separating biomass components by using ternary eutectic solvent | 华东理工大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-115785416-B | Poly (ethylene glycol-co-diethylene glycol) oxalate and preparation method thereof | 新倍斯(杭州)材料科技有限公司 | 2024-01-19 | — | — | CN | disclosed |
| US-20230321202-A1 | AMERICAN CHESTNUT LEAF COMPOSITIONS COMPRISING OXALATE OXIDASE AND METHODS FOR TREATMENT OF OXALATE-RELATED DISORDERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2023-10-12 | — | — | US | disclosed |
| CN-116836522-A | Seawater-degradable PBAT polyester composition, preparation method and application | 大连理工大学 | 2023-10-03 | — | — | CN | disclosed |
| CN-107673974-B | Recycling method and device for nitrogen oxides | 上海华谊能源化工有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-107673974-B | Recycling method and device for nitrogen oxides | 上海华谊能源化工有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116694039-A | High-barrier-property PBAT composition, preparation method and application | 大连理工大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-115785406-B | Preparation method of kilogram-level polyethylene glycol oxalate | 新倍斯(杭州)材料科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-115785406-B | Preparation method of kilogram-level polyethylene glycol oxalate | 新倍斯(杭州)材料科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-115785410-B | High-thermal-stability polyethylene glycol oxalate copolyester and preparation method thereof | 新倍斯(杭州)材料科技有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-115785406-A | Preparation method of kilogram-grade polyethylene glycol oxalate | 新倍斯(杭州)材料科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-115785416-A | Poly (ethylene glycol-co-diethylene glycol) oxalate and preparation method thereof | 新倍斯(杭州)材料科技有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-114108350-B | Method for quickly separating main components of wood biomass by using eutectic solvent | 北京林业大学 | 2023-02-17 | — | — | CN | disclosed |
| CN-115569234-A | Basalt fiber pipe sleeve for prosthetic socket and preparation method thereof | 北京连续玄武岩纤维科技有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-115527436-A | Metal work card sprayed with acrylic paint information and cleaning method thereof | 深圳市中孚能电气设备有限公司 | 2022-12-27 | — | — | CN | disclosed |
| US-20220403361-A1 | CRYSTALLIZED OXALATE DECARBOXYLASE AND METHODS OF USE | GLYSCEND, INC. | 2022-12-22 | — | — | US | disclosed |
| CN-115487874-A | Metallurgical slag-based carbon monoxide low-temperature oxidation catalyst, and preparation method and application thereof | 上海交通大学 | 2022-12-20 | — | — | CN | disclosed |
| US-20220340513-A1 | PROCESS FOR PREPARING DIALKYL CARBONATE AND ALKANEDIOL | SHELL USA, INC | 2022-10-27 | — | — | US | disclosed |
| CN-113411920-B | Heating carbon slurry and preparation method thereof | 嘉兴学院 | 2022-08-19 | — | — | CN | disclosed |
| EP-4038046-A1 | PROCESS FOR PREPARING DIALKYL CARBONATE AND ALKANEDIOL | Shell Internationale Research Maatschappij B.V. (NL) | 2022-08-10 | — | — | EP | disclosed |
| CN-113527644-B | Preparation method of high molecular weight poly (hexanediol oxalate) | 河北大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-111576092-B | Method for manufacturing tipping paper for cigarettes with lasting normal sweetness | 江苏中烟工业有限责任公司 | 2022-05-24 | — | — | CN | disclosed |
| CN-111519464-B | Sweetener composition for dry food packaging paper | 江苏中烟工业有限责任公司 | 2022-05-17 | — | — | CN | disclosed |
| US-20220133865-A1 | CRYSTALLIZED OXALATE DECARBOXYLASE AND METHODS OF USE | GLYSCEND, INC. | 2022-05-05 | — | — | US | disclosed |
| CN-114108350-A | Method for quickly separating main components of wood biomass by using eutectic solvent | 北京林业大学 | 2022-03-01 | — | — | CN | disclosed |
| CN-113527644-A | Preparation method of high molecular weight poly (hexanediol oxalate) | 河北大学 | 2021-10-22 | — | — | CN | disclosed |
| CN-113512185-A | Thermoplastic biodegradable glove material and preparation method thereof | 江南大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-113411920-A | Heating carbon slurry and preparation method thereof | 嘉兴学院 | 2021-09-17 | — | — | CN | disclosed |
| CN-112920756-A | Residual-free moisture-cured adhesive and preparation method thereof | 浙江洛克新材料股份有限公司 | 2021-06-08 | — | — | CN | disclosed |
| WO-2021063853-A1 | PROCESS FOR PREPARING DIALKYL CARBONATE AND ALKANEDIOL | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2021-04-08 | — | — | WO | disclosed |
| CN-112601519-A | Loadable porous structures for use as implants | 泰坦医药品公司 | 2021-04-02 | — | — | CN | disclosed |
| CN-105555950-B | Cell populations, methods of transdifferentiation and methods of use thereof | 奥尔吉尼西丝有限公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-112313258-A | Transparent rigid thermoplastic polyurethanes | 巴斯夫欧洲公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-111576092-A | Method for manufacturing tipping paper for cigarettes with lasting normal sweetness | 江苏中烟工业有限责任公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-111519464-A | Sweetener composition for dry food packaging paper | 江苏中烟工业有限责任公司 | 2020-08-11 | — | — | CN | disclosed |
| CN-111153788-A | Method for preparing organic acid through organic alcohol dehydrogenation reaction and method for thermodynamically controlling organic alcohol dehydrogenation reaction | 中国科学院大连化学物理研究所 | 2020-05-15 | — | — | CN | disclosed |
| CN-110628104-A | Preparation method of high-solid-content carboxylic butyronitrile latex | 东营九洲奥华化工有限责任公司 | 2019-12-31 | — | — | CN | disclosed |
| CN-110574128-A | Insulated wire | 住友电气工业株式会社 | 2019-12-13 | — | — | CN | disclosed |
| CN-209619242-U | The recovery system of synthesis gas preparing ethylene glycol oxalate process byproduct methyl formate | PUYANG ZHIFENG CHEMICAL CO LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-209619242-U | The recovery system of synthesis gas preparing ethylene glycol oxalate process byproduct methyl formate | PUYANG ZHIFENG CHEMICAL CO LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-209619242-U | The recovery system of synthesis gas preparing ethylene glycol oxalate process byproduct methyl formate | PUYANG ZHIFENG CHEMICAL CO LTD | 2019-11-12 | — | — | CN | disclosed |
| US-10335370-B2 | Controlled release composition | XU JIANJIAN (CN) | 2019-07-02 | — | — | US | disclosed |
| CN-109364510-A | The device of high-purity methyl formate is extracted from the by-product of preparation of ethanediol by dimethyl oxalate hydrogenation | 中盐安徽红四方股份有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-207596755-U | A kind of recycling plant of nitrogen oxides | 上海华谊能源化工有限公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-207596755-U | A kind of recycling plant of nitrogen oxides | 上海华谊能源化工有限公司 | 2018-07-10 | — | — | CN | disclosed |
| CN-107787342-A | Durable icephobic surfaces | 密执安州立大学董事会 | 2018-03-09 | — | — | CN | disclosed |
| CN-107673974-A | The recycling method and device of a kind of nitrogen oxides | 上海华谊能源化工有限公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-107673974-A | The recycling method and device of a kind of nitrogen oxides | 上海华谊能源化工有限公司 | 2018-02-09 | — | — | CN | disclosed |
| CN-107108864-A | The manufacture method of aliphatic polyester composition and article shaped and aliphatic polyester | 株式会社吴羽 | 2017-08-29 | — | — | CN | disclosed |
| CN-105040073-B | A kind of method that use two-step anodization prepares ceria film | 上海应用技术学院 | 2017-06-23 | — | — | CN | disclosed |
| CN-105088317-B | A kind of preparation method of ceria film | 上海应用技术学院 | 2017-05-31 | — | — | CN | disclosed |
| US-20170035695-A1 | NOVEL CONTROLLED RELEASE COMPOSITION | XU JIANJIAN (CN) | 2017-02-09 | — | — | US | disclosed |
| US-9498431-B2 | Controlled releasing composition | XU JIANJIAN (CN) | 2016-11-22 | — | — | US | disclosed |
| CN-105088317-A | Preparation method of ceria film | SHANGHAI INST TECHNOLOGY | 2015-11-25 | — | — | CN | disclosed |
| CN-105040073-A | Method for preparing ceric oxide membrane through two-step anodic oxidation | SHANGHAI INST TECHNOLOGY | 2015-11-11 | — | — | CN | disclosed |
| CN-104231717-A | Oil paint stripping agent and preparation method thereof | JING LI | 2014-12-24 | — | — | CN | disclosed |
| CN-102432686-B | Micro-nano cellulose and preparation method thereof | UNIV FUJIAN AGRIC & FORESTRY | 2013-06-19 | — | — | CN | disclosed |
| CN-102432686-A | Micro-nano cellulose and preparation method thereof | UNIV FUJIAN AGRIC & FORESTRY | 2012-05-02 | — | — | CN | disclosed |
| CN-102418278-A | Preparation method of cationic polyurethane antistatic agent for terylene | WUJIANG BEIKU SHENGYUAN TEXTILE PRODUCT AUXILIARIES FACTORY | 2012-04-18 | — | — | CN | disclosed |
| EP-2379059-A1 | CONTROLLED RELEASING COMPOSITION | Anhui Zhongren Technology Co., Ltd. (CN) | 2011-10-26 | — | — | EP | disclosed |
| US-8041070-B2 | Speaker | HOSIDEN CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20110244043-A1 | Controlled releasing composition | XU JIANJIAN | 2011-10-06 | — | — | US | disclosed |
| CN-1974662-B | Composite elastic chitin whisker material and its prepn and use | UNIV CHINA GEOSCIENCES WUHAN | 2010-12-08 | — | — | CN | disclosed |
| WO-2010066203-A1 | CONTROLLED RELEASING COMPOSITION | ANHUI ZHONGREN TECHNOLOGY CO., LTD. (CN) | 2010-06-17 | — | — | WO | disclosed |
| CN-1974662-A | Composite elastic chitin whisker material and its prepn and use | CHINA GEOLOGY UNIV WUAHN (CN) | 2007-06-06 | — | — | CN | disclosed |
| CN-1556827-A | Targeted hydrophilic polymers, conjugates thereof with interferons, and pharmaceutical compositions comprising the same | ƽ | 2004-12-22 | — | — | CN | disclosed |
| CN-1556827-A | Targeted hydrophilic polymers, conjugates thereof with interferons, and pharmaceutical compositions comprising the same | ƽ | 2004-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220133865-A1 | CRYSTALLIZED OXALATE DECARBOXYLASE AND METHODS OF USE | UROD, OTC, ODC1 | TSHR 4701/4885OR51E2 1972/4885CAMK2A 1876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.