Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4680528 | 0.84 | TBXAS1 (0.32) | CHRNB2CHRNA4SMN1; SMN2TBXAS1LMNA | |
| SCHEMBL4681113 | 0.80 | TRPA1 (0.31) | — | |
| SCHEMBL4684491 | 0.78 | MKNK1 (0.39) | SMN1; SMN2KDM4EMKNK1MKNK2CYP2A6 | |
| SCHEMBL4681569 | 0.75 | MKNK1 (0.37) | SMN1; SMN2KDM4EMKNK1MKNK2TBXAS1 | |
| SCHEMBL19219854 | 0.74 | CHRNB2 (0.39) | CHRNB2CHRNA4SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4681696 | 0.72 | TBXAS1 (0.37) | CHRNB2CHRNA4SMN1; SMN2KDM4EMKNK1 | |
| SCHEMBL19091523 | 0.71 | TDP1 (0.44) | CHRNB2CHRNA4L3MBTL1CYP2A6 | |
| SCHEMBL7351528 | 0.71 | TRPA1 (0.32) | — | |
| SCHEMBL4684862 | 0.71 | TBXAS1 (0.39) | SMN1; SMN2KDM4EMKNK1MKNK2TBXAS1 | |
| SCHEMBL4681773 | 0.71 | CYP1A2 (0.35) | CHRNB2CHRNA4SMN1; SMN2LMNACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |