Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.67 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.48 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13801215 | 0.86 | AOC3 (0.65) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL4526552 | 0.83 | CALM1 (0.54) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL44276 | 0.83 | AOC3 (0.75) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL18122711 | 0.83 | AOC3 (0.75) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL8508344 | 0.81 | AOC3 (0.73) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL4680668 | 0.79 | AOC3 (0.69) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL723511 | 0.78 | TAAR1 (0.77) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL30080050 | 0.78 | TAAR1 (0.77) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL555038 | 0.77 | AOC3 (0.66) | AOC3TAAR1SIGMAR1CHRM2CHRM1 | |
| SCHEMBL5271881 | 0.77 | AOC3 (0.66) | AOC3TAAR1SIGMAR1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B8 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-08-27 | — | — | EP | disclosed |
| EP-1416933-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgem, Inc. (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003009847-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM, INC. (US) | 2003-02-06 | — | — | WO | disclosed |