Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 14/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | PDE1A | P54750 | 2/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640501 | 0.90 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL16252260 | 0.83 | UCHL1 (0.54) | NPBWR1MCHR1PDE1APDE1BPDE1C | |
| SCHEMBL25723425 | 0.82 | NPBWR1 (0.64) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL4679664 | 0.80 | NPBWR1 (0.61) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL25756148 | 0.80 | NPBWR1 (0.61) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL29731534 | 0.80 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL29731573 | 0.80 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL29102671 | 0.80 | NPBWR1 (0.68) | NPBWR1MCHR1PKM | |
| SCHEMBL25756143 | 0.79 | NPBWR1 (0.63) | NPBWR1MCHR1PKMPKLRPDE1A | |
| SCHEMBL4680318 | 0.77 | NPBWR1 (0.57) | NPBWR1MCHR1PKMPKLRPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045836-B1 | PYRIDONES AS SRC FAMILY SH2 DOMAIN INHIBITORS | BOEHRINGER INGELHEIM PHARMA (US) | 2008-03-05 | — | — | EP | disclosed |
| US-6284768-B1 | Src family SH2 domain inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2001-09-04 | — | — | US | disclosed |
| US-6268365-B1 | Src family SH2 domain inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2001-07-31 | — | — | US | disclosed |
| EP-1045836-A1 | PYRIDONES AS SRC FAMILY SH2 DOMAIN INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2000-10-25 | — | — | EP | disclosed |
| US-6054470-A | Src family SH2 domain inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2000-04-25 | — | — | US | disclosed |
| WO-1999031066-A1 | PYRIDONES AS SRC FAMILY SH2 DOMAIN INHIBITORS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-06-24 | — | — | WO | disclosed |