Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4677787 | 0.80 | — | — | |
| SCHEMBL4680875 | 0.80 | GRK6 (0.53) | — | |
| SCHEMBL4680998 | 0.79 | XDH (0.50) | — | |
| SCHEMBL4680659 | 0.76 | — | — | |
| SCHEMBL4676332 | 0.75 | — | — | |
| SCHEMBL4677413 | 0.72 | — | — | |
| SCHEMBL4676957 | 0.72 | — | — | |
| SCHEMBL8488406 | 0.71 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL4684074 | 0.70 | — | — | |
| SCHEMBL4677409 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471065-B1 | NOVEL 1,2,4-TRIAZOLE COMPOUND | FUJI YAKUHIN CO LTD (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-7074816-B2 | 1 2 4-triazole compound | FUJI YAKUHIN CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20050004175-A1 | Novel 1 2 4-triazole compound | FUJI YAKUHIN CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1471065-A1 | NOVEL 1,2,4-TRIAZOLE COMPOUND | Fuji Yakuhin Co., Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004175-A1 | Novel 1 2 4-triazole compound | XDH, PNPO, NOX1 | CHEK1 3354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.