Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683524 | 0.95 | MCHR1 (0.41) | MCHR1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL4687113 | 0.91 | KMT2A (0.43) | MCHR1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4683021 | 0.90 | TRPV1 (0.37) | MCHR1TRPV1ALDH1A1MAPTKMT2A | |
| SCHEMBL4683520 | 0.82 | PKM (0.39) | MCHR1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL4688079 | 0.81 | MAPT (0.42) | MCHR1ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL4683459 | 0.80 | MAPT (0.45) | MCHR1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4687107 | 0.79 | MAPT (0.41) | MCHR1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL4232410 | 0.78 | PKM (0.39) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL4684667 | 0.78 | TOP2A (0.44) | ALDH1A1MAPTKMT2AMEN1NAMPT | |
| SCHEMBL4686821 | 0.78 | CHRM4 (0.48) | MCHR1ALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |