Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683524 | 0.92 | MCHR1 (0.41) | KMT2AMCHR1MAPTMEN1EPHX1 | |
| SCHEMBL4683022 | 0.91 | MCHR1 (0.40) | KMT2AMCHR1MAPTMEN1EPHX1 | |
| SCHEMBL4687107 | 0.88 | MAPT (0.41) | KMT2AMCHR1MAPTMEN1NPC1 | |
| SCHEMBL4686821 | 0.82 | CHRM4 (0.48) | KMT2AMCHR1MAPTMEN1NPC1 | |
| SCHEMBL4683021 | 0.81 | TRPV1 (0.37) | KMT2AMCHR1MAPTMEN1ALDH1A1 | |
| SCHEMBL4688079 | 0.80 | MAPT (0.42) | KMT2AMCHR1MAPTALDH1A1 | |
| SCHEMBL4683520 | 0.79 | PKM (0.39) | KMT2AMCHR1MAPTMEN1NPC1 | |
| SCHEMBL4683459 | 0.77 | MAPT (0.45) | KMT2AMCHR1MAPTMEN1NPC1 | |
| SCHEMBL4686962 | 0.76 | CACNA1B (0.51) | KMT2AMCHR1MAPTMEN1NPC1 | |
| SCHEMBL4232410 | 0.76 | PKM (0.39) | KMT2AMAPTMEN1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |