Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.65 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19611839 | 0.89 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL2762349 | 0.87 | POLB (0.62) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL7134591 | 0.82 | PLA2G10 (0.83) | PLA2G10PLA2G2AALDH1A1L3MBTL1KMT2A | |
| SCHEMBL4683087 | 0.81 | MAPT (0.55) | ALDH1A1KMT2AMEN1RAB9APOLB | |
| SCHEMBL3773254 | 0.81 | SLC1A3 (0.58) | PLA2G10PLA2G2AALDH1A1KMT2AMEN1 | |
| SCHEMBL1719129 | 0.79 | PLA2G2A (1.00) | PLA2G10PLA2G2AL3MBTL1KMT2ACYP17A1 | |
| SCHEMBL28945385 | 0.78 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL12663746 | 0.77 | PLA2G10 (0.68) | PLA2G10PLA2G2AALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1837826 | 0.77 | PEPD (0.61) | ALDH1A1KMT2AMEN1NPC1POLB | |
| Phenol SCHEMBL663964 | 0.76 | MAOA (0.53) | ALDH1A1KMT2AKDM4EMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843295-A | NAMPT modulators | 赛特凯恩蒂克公司 | 2023-03-24 | — | — | CN | disclosed |