SCHEMBL4683271

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16578231	1.00	SLC7A5 (0.43)	SLC7A5CTSBALDH1A1THRBCYP2C9
	SCHEMBL14501406	0.86	PPARG (0.47)	SLC7A5CTSBMEN1KMT2AFOLH1
	SCHEMBL16574787	0.83	SLC7A5 (0.52)	SLC7A5CTSBALDH1A1IDO1OPRK1
	SCHEMBL2496147	0.83	NLRP3 (0.50)	SLC7A5ALDH1A1THRBCYP2C9CYP2C19
	SCHEMBL27810401	0.83	NLRP3 (0.50)	SLC7A5ALDH1A1THRBCYP2C9CYP2C19
	SCHEMBL6028187	0.83	TAAR1 (0.54)	SLC7A5MEN1KMT2ASLC6A3LOXL2
	SCHEMBL2500604	0.83	NLRP3 (0.50)	SLC7A5ALDH1A1THRBCYP2C9CYP2C19
	SCHEMBL8802162	0.83	ALDH1A1 (0.47)	SLC7A5ALDH1A1THRBCYP2C9CYP2C19
	SCHEMBL972579	0.82	PLA2G10 (0.47)	CTSBCYP2C19FOLH1
	SCHEMBL4679627	0.82	FOLH1 (0.48)	SLC7A5CTSBMEN1KMT2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.