Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 4/20 | 0.49 |
| ▸ | RAF1 | P04049 | 5/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 2/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686596 | 0.90 | CCR3 (0.57) | CCR3CCR2KDRBRAFMAPT | |
| SCHEMBL4686982 | 0.89 | CCR3 (0.49) | CCR3CCR2MAPTOPRM1OPRD1 | |
| SCHEMBL4234052 | 0.89 | EPHX2 (0.43) | CCR3RAF1EPHX2SLC6A5UBE2M | |
| SCHEMBL4683553 | 0.89 | CCR3 (0.49) | CCR3EPHX2CCR2UBE2MDCUN1D1 | |
| SCHEMBL4683722 | 0.89 | MAPT (0.49) | CCR3MAPTOPRM1OPRD1MEN1 | |
| SCHEMBL4688476 | 0.88 | CCR3 (0.51) | CCR3CCR2SLC6A5MAPTOPRM1 | |
| SCHEMBL4688687 | 0.87 | CCR3 (0.48) | CCR3CCR2MAPTOPRM1OPRD1 | |
| SCHEMBL4683919 | 0.85 | CCR3 (0.50) | CCR3CCR2SLC6A5KDRMAPT | |
| SCHEMBL4683393 | 0.84 | FGFR1 (0.48) | CCR3KDRMAPTOPRM1OPRD1 | |
| SCHEMBL4686354 | 0.84 | CCR3 (0.46) | CCR3EPHX2MAPTOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |