SCHEMBL4683567

SCHEMBL4683567

C#CCN1C(=O)COc2cc(F)c(NN)cc21

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 2/20 0.37
POLB P06746 1/20 0.37
CHRM5 P08912 1/20 0.34
CHRM3 P20309 1/20 0.34
PLK1 P53350 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9224359 0.84 POLB (0.43) CHRM1POLBPLK1TSHRHTT
SCHEMBL30010421 0.84 CHRM1 (0.37) CHRM1POLBCHRM5CHRM3PLK1
SCHEMBL6724624 0.84 CHRM1 (0.37) CHRM1POLBCHRM5CHRM3PLK1
SCHEMBL29136558 0.82 CHRM1 (0.38) CHRM1POLBCHRM5CHRM3PLK1
SCHEMBL9228447 0.82 POLB (0.44) CHRM1POLBPLK1TSHR
SCHEMBL9031064 0.82 POLB (0.44) CHRM1POLBPLK1TSHRHTT
SCHEMBL6831854 0.81 POLB (0.38) CHRM1POLBPLK1TSHRHTT
SCHEMBL9727365 0.80 POLB (0.44) CHRM1POLBPLK1TSHRHTT
SCHEMBL7687650 0.79 CHRM1 (0.40) CHRM1POLBCHRM5CHRM3TSHR
SCHEMBL303837 0.79 POLB (0.36) CHRM1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850227-B1 PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2008-01-09 EP disclosed
US-6869913-B1 Pyridazin-3-one derivatives, their use and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-03-22 US disclosed
US-6703503-B2 HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-09 US disclosed
US-20040005986-A1 Pyridazin-3-one derivatives, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2004-01-08 US disclosed
US-6482773-B1 Pyridazin-3-one derivatives, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-19 US disclosed
US-6348628-B1 HYDRAZONE HERBICIDE INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
US-6090753-A 2-(SUBSTITUTED PHENYL), 5-HALOALKYL-PYRIDAZIN-3-ONE DERIVATIVES AS HERBICIDES; CONTROLLING WEEDS, METHOD OF MAKING BY REACTING A HYDRAZONE DERIVATIVE WITH A SPECIFIED PHOSPHORUS COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2000-07-18 US disclosed
EP-0850227-A1 PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-01 EP disclosed
WO-1997007104-A1 PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-27 WO disclosed
EP-0305923-B1 BENZOXAZINYL-TRIAZOLE OXIDES, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-07-29 EP disclosed
EP-0304935-B1 TETRAHYDROINDAZOLYL-BENZOXAZINES, THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-10-30 EP disclosed
US-4970322-A Etherification; Herbicides SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1990-11-13 US disclosed
US-4954626-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-09-04 US disclosed
US-4885024-A HERBICIDES SUMITOMO CHEMICAL CO., LTD. (JP) 1989-12-05 US disclosed
US-4877444-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-10-31 US disclosed
EP-0305923-A1 Benzoxazinyl-triazole oxides, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-03-08 EP disclosed
EP-0304935-A1 Tetrahydroindazolyl-benzoxazines, their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-03-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040005986-A1 Pyridazin-3-one derivatives, their use, and intermediates for their production Q6ZSR9, HDHD5, CBR3 CHRM1 264/4885POLB 1381/4885CHRM5 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.