Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.49 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233484 | 0.91 | CACNA1B (0.52) | CACNA1BAPBA1SAE1UBA2MAPK14 | |
| SCHEMBL4686962 | 0.83 | CACNA1B (0.51) | CACNA1BAPBA1SAE1UBA2MAPK14 | |
| SCHEMBL4689202 | 0.82 | SMN1; SMN2 (0.40) | LMNASMN1; SMN2KMT2AHSD17B10MAPT | |
| SCHEMBL4236949 | 0.81 | KMT2A (0.52) | RAB9ANPC1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4232732 | 0.80 | MCHR1 (0.44) | CACNA1BAPBA1SAE1UBA2RAB9A | |
| SCHEMBL4240328 | 0.79 | LTA4H (0.51) | CACNA1BAPBA1SAE1UBA2RAB9A | |
| SCHEMBL4234367 | 0.77 | SSTR5 (0.42) | CACNA1BAPBA1SAE1UBA2KMT2A | |
| SCHEMBL4687213 | 0.77 | MCHR1 (0.42) | RAB9ANPC1LMNASMN1; SMN2KMT2A | |
| SCHEMBL4238693 | 0.77 | CHRM4 (0.47) | CACNA1BAPBA1SAE1UBA2RAB9A | |
| SCHEMBL4228379 | 0.76 | MCHR1 (0.41) | CACNA1BAPBA1SAE1UBA2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |