Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.51 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233484 | 0.86 | CACNA1B (0.52) | CACNA1BAPBA1SAE1UBA2L3MBTL1 | |
| SCHEMBL4688079 | 0.85 | MAPT (0.42) | MCHR1RAB9AMAPTLMNAKMT2A | |
| SCHEMBL4686821 | 0.84 | CHRM4 (0.48) | CACNA1BAPBA1SAE1UBA2L3MBTL1 | |
| SCHEMBL4683677 | 0.83 | CACNA1B (0.49) | CACNA1BAPBA1SAE1UBA2L3MBTL1 | |
| SCHEMBL4683722 | 0.82 | MAPT (0.49) | MCHR2MCHR1MAPTLMNASMN1; SMN2 | |
| SCHEMBL4683469 | 0.81 | MCHR1 (0.52) | L3MBTL1MCHR2MCHR1NPC1MAPT | |
| SCHEMBL4682919 | 0.79 | HDAC1 (0.51) | NPC1RAB9AMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4686354 | 0.78 | CCR3 (0.46) | MCHR2MCHR1MAPTLMNAKMT2A | |
| SCHEMBL4683401 | 0.78 | CHRM4 (0.51) | L3MBTL1MCHR2MCHR1NPC1RAB9A | |
| SCHEMBL4787221 | 0.77 | EPHX1 (0.52) | MCHR1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |