Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.76 |
| ▸ | CES2 | O00748 | 2/20 | 0.76 |
| ▸ | FNTA | P49354 | 2/20 | 0.61 |
| ▸ | FNTB | P49356 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | C1S | P09871 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylpyruvate SCHEMBL11297524 | 0.98 | CES1 (0.73) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL43235 | 0.97 | CES1 (0.80) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28203540 | 0.97 | CES1 (0.80) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28232350 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28233232 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL27281240 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL9217988 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL11193388 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL3408866 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28233246 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106366114-A | 2-Oxo-3-phenylpropionic acid p-methylbenzoyl hydrazone dibenzyltin complex, and preparation method and application thereof | 衡阳师范学院 | 2017-02-01 | — | — | CN | claimed |
| CN-106279261-A | A kind of 2 carbonyl 3 phenylpropionic acids are to toluyl hydrazone di-n-butyl tin coordination compound and its preparation method and application | 衡阳师范学院 | 2017-01-04 | — | — | CN | claimed |
| WO-2009018368-A1 | COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2009-02-05 | — | — | WO | claimed |
| EP-4206322-A2 | POLYPEPTIDE AND METHOD FOR PRODUCING AMINO ACID USING SAME | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-11529342-B2 | Sorbic and benzoic acid and derivatives thereof enhance the activity of a neuropharmaceutical | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2022-12-20 | — | — | US | disclosed |
| US-20220204918-A1 | CELL CULTURE MEDIA COMPRISING KETO ACIDS | MERCK PATENT GMBH (DE) | 2022-06-30 | — | — | US | disclosed |
| CN-113461508-A | Preparation method of alpha-ketophenylalanine calcium | 北京福元医药股份有限公司沧州分公司 | 2021-10-01 | — | — | CN | disclosed |
| EP-3006023-B1 | SORBIC ACID AND DERIVATIVES THEREOF TO ENHANCE THE ACTIVITY OF A NEUROPHARMACEUTICAL | LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) | 2019-06-26 | — | — | EP | disclosed |
| US-20190151301-A1 | SORBIC AND BENZOIC ACID AND DERIVATIVES THEREOF ENHANCE THE ACTIVITY OF A NEUROPHARMACEUTICAL | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2019-05-23 | — | — | US | disclosed |
| EP-3006024-B1 | BENZOIC ACID OR SALTS THEREOF TO ENHANCE THE ACTIVITY OF A NEUROPHARMACEUTICAL | LOS ANGELES BIOMEDICAL RES INST HARBOR UCLA MEDICAL CT (US) | 2019-03-20 | — | — | EP | disclosed |
| US-10149845-B2 | Sorbic and benzoic acid and derivatives thereof enhance the activity of a neuropharmaceutical | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2018-12-11 | — | — | US | disclosed |
| CN-1049650-C | Synthetic method of phenyl-pyruvic alkali salt and ammonium salt | NANJING CHEMICAL ENGINEERING U (CN) | 2000-02-23 | — | — | CN | disclosed |
| CN-1138022-A | Synthetic method of phenyl-pyruvic alkali salt and ammonium salt | NANJING CHEMICAL ENGINEERING U (CN) | 1996-12-18 | — | — | CN | disclosed |
| EP-0395124-B1 | Process for producing L-phenylalanine | KYOWA HAKKO KOGYO KK (JP) | 1994-06-01 | — | — | EP | disclosed |
| EP-0151488-B1 | PROCESS FOR PRODUCING L-PHENYLALANINE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |
| EP-0395124-A1 | Process for producing L-phenylalanine | KYOWA HAKKO KOGYO CO., LTD (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4859591-A | Transamination process for producing amino acids | W. R. GRACE & CO.-CONN. (US) | 1989-08-22 | — | — | US | disclosed |
| US-4783403-A | FROM PHENYLPYRUVIC ACID AND AMINO GROUP DONOR USING MICRO-ORGANISM | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1988-11-08 | — | — | US | disclosed |
| US-4584399-A | ADSORBING IN ACTIVATED CARBON, ELUTING, PASSING THRU ION ECCHANGER | W. R. GRACE & CO. (US) | 1986-04-22 | — | — | US | disclosed |
| EP-0151488-A2 | Process for producing L-phenylalanine | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-08-14 | — | — | EP | disclosed |