Phenylpyruvate

Phenylpyruvate

SCHEMBL43235

O=C(O)C(=O)Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.80
CES2 O00748 2/20 0.80
FNTA P49354 2/20 0.64
FNTB P49356 2/20 0.64
AKR1B1 P15121 1/20 0.64
F2 P00734 2/20 0.57
CTBP2 P56545 1/20 0.56
PLG P00747 1/20 0.55
PRSS1 P07477 1/20 0.55
PRSS2 P07478 1/20 0.55
C1S P09871 1/20 0.55
PRSS3 P35030 1/20 0.55
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
CYP3A4 P08684 1/20 0.52
CYP2C9 P11712 1/20 0.52
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylpyruvate SCHEMBL28203540 1.00 CES1 (0.80) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28233246 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28233232 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL27281240 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL9217988 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL11193388 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL28232350 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL3408866 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL468389 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1
Phenylpyruvate SCHEMBL6850951 0.97 CES1 (0.76) CES1CES2FNTAFNTBAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8366 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122080382-A Isosorbide type polycarbonate and preparation method thereof 2026-05-26 CN claimed
EP-3869192-B1 METHOD FOR QUANTITATIVE DETECTION OF VARIOUS METABOLITES IN BIOLOGICAL SAMPLE HUMAN METABOLOMICS INST INC (CN) 2026-05-13 EP claimed
US-20260123658-A1 Methods of Increasing the Beneficial Properties of Fermented Foods The Brd. of Trustees of the Univ. of Illinois (US) 2026-05-07 US claimed
EP-3796922-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING A SELENO AMINO ACID COMPOUND FOR USE IN COMBINATION WITH ANOTHER AGENT FOR THE TREATMENT OF LIVER OR PANCREAS CANCER SELEQ OY (FI) 2026-03-18 EP claimed
EP-4709912-A1 PROTEIN THERAPEUTICS FOR TREATMENT OF SENESCENT CELLS BioAtla, Inc. (US) 2026-03-18 EP claimed
US-20260028562-A1 FLAVORED POROUS MATERIAL FOR FLAVORED BEVERAGE PRODUCTION DANSTAR FERMENT AG (CH) 2026-01-29 US claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
EP-4644540-A1 ENZYME, STRAIN FOR PRODUCING SALIDROSIDE, AND PRODUCTION METHOD Bloomage Biotechnology Corporation Limited (CN) 2025-11-05 EP claimed
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials FIRMENICH SA (CH) 2025-10-07 US claimed
EP-0000645-A1 Isopenicillins, processes for their preparation, and compositions containing them SMITHKLINE BECKMAN CORPORATION (US) 1979-02-07 EP claimed
US-4122086-A Isopenicillins SMITHKLINE CORPORATION (US) 1978-10-24 US claimed
US-4118566-A Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-10-03 US claimed
US-4113946-A Δ2,3 -1,4-Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-12 US claimed
US-4112230-A Δ2,3 -1,4 Morpholine-2-carboxylic acid derivatives as antibacterial agents BRISTOL-MYERS COMPANY (US) 1978-09-05 US claimed
US-4105782-A REACTION PRODUCT OF AN ACID AND AMMONIUM HYDROXIDE OR AN AMINE YU RUEY J 1978-08-08 US claimed
US-4105783-A Therapeutic treatment of dry skin YU RUEY J 1978-08-08 US claimed
US-4100293-A Treatment of hepatic disorders with therapeutic compositions comprising keto analogs of essential amino acids THE JOHNS HOPKINS UNIVERSITY (US) 1978-07-11 US claimed
US-4093625-A 6-Sulfur analogs of penicillins and cephalosporins MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1978-06-06 US claimed
US-3984401-A Process for producing lactol-type cephalosporins TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1976-10-05 US claimed