Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.76 |
| ▸ | CES2 | O00748 | 2/20 | 0.76 |
| ▸ | FNTA | P49354 | 2/20 | 0.61 |
| ▸ | FNTB | P49356 | 2/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | C1S | P09871 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylpyruvate SCHEMBL43235 | 0.97 | CES1 (0.80) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28203540 | 0.97 | CES1 (0.80) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28232350 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28233246 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL28233232 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL468389 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL27281240 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL9217988 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL11193388 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 | |
| Phenylpyruvate SCHEMBL6850951 | 0.95 | CES1 (0.76) | CES1CES2FNTAFNTBAKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020244798-A1 | METHOD FOR TASTE/ODOR MASKING OF A PRODUCT FOR CHRONIC KIDNEY DISEASE PATIENTS | ATHENION AG (CH) | 2020-12-10 | — | — | WO | claimed |
| CN-109588554-A | It is a kind of to utilize waste bamboo shell solid state fermentation production biological feedstuff and preparation method thereof | 浙江皇冠科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-108384210-A | A kind of application of pyruvates and polydactyl acid | 中国科学院长春应用化学研究所 | 2018-08-10 | — | — | CN | claimed |
| WO-2012137216-A1 | A NOVEL PHARMACEUTICAL FORMULATION OF ALPHA KETOANALOGUE OF AMINO ACIDS AND ADDITIONAL AMINO ACIDS FOR TREATMENT OF CHRONIC KIDNEY DISEASE AND METHOD OF PREPARATION THEREOF | RPG LIFE SCIENCES LIMITED (IN) | 2012-10-11 | — | — | WO | claimed |
| WO-2009018368-A1 | COMBINATION TREATMENT OF NMDA (N-METHYL-D-ASPARTATE)-ENHANCER, GLYCINE TRANSPORTER INHIBITOR, D-AMINO ACID OXIDASE INHIBITOR (DAAOI) FOR NEUROPSYCHIATRIC DISORDERS | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (US) | 2009-02-05 | — | — | WO | claimed |
| CN-1049650-C | Synthetic method of phenyl-pyruvic alkali salt and ammonium salt | NANJING CHEMICAL ENGINEERING U (CN) | 2000-02-23 | — | — | CN | claimed |
| CN-1138022-A | Synthetic method of phenyl-pyruvic alkali salt and ammonium salt | NANJING CHEMICAL ENGINEERING U (CN) | 1996-12-18 | — | — | CN | claimed |
| EP-0422162-A4 | PROCESS FOR PREPARING SODIUM PHENYLPYRUVATE FROM CALCIUM PHENYLPYRUVATE | — | 1991-09-25 | — | — | EP | claimed |
| EP-0422162-A1 | PROCESS FOR PREPARING SODIUM PHENYLPYRUVATE FROM CALCIUM PHENYLPYRUVATE | THE NUTRASWEET COMPANY (US) | 1991-04-17 | — | — | EP | claimed |
| US-4997979-A | Carbonylation, cobalt catalyst | RHONE-POULENC CHIMIE (FR) | 1991-03-05 | — | — | US | claimed |
| WO-1990011993-A1 | PROCESS FOR PREPARING SODIUM PHENYLPYRUVATE FROM CALCIUM PHENYLPYRUVATE | THE NUTRASWEET COMPANY (US) | 1990-10-18 | — | — | WO | claimed |
| US-4912255-A | Process for preparing sodium phenylpyruvate from calcium phenylpyruvate | NUTRASWEET COMPANY, THE | 1990-03-27 | — | — | US | claimed |
| US-4100161-A | Promotion of protein synthesis and suppression of urea formation in the body by keto analogs of essential amino acids | THE JOHNS HOPKINS UNIVERSITY (US) | 1978-07-11 | — | — | US | claimed |
| US-4100160-A | Therapeutic compositions comprising alpha-hydroxy analogs of essential amino acids and their administration to humans for promotion of protein synthesis and suppression of urea formation | THE JOHNS HOPKINS UNIVERSITY (US) | 1978-07-11 | — | — | US | claimed |
| JP-2022246-A | — | — | None | — | — | JP | disclosed |
| US-20240258529-A1 | SECONDARY BATTERY AND PREPARATION METHOD THEREOF, BATTERY MODULE, BATTERY PACK AND POWERED DEVICE | CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITED (CN) | 2024-08-01 | — | — | US | disclosed |
| EP-4398348-A1 | SECONDARY BATTERY AND MANUFACTURING METHOD THEREFOR, BATTERY MODULE, BATTERY PACK AND ELECTRICAL DEVICE | Contemporary Amperex Technology Co., Limited (CN) | 2024-07-10 | — | — | EP | disclosed |
| JP-H0222246-A | PRODUCTION OF ALKALI PHENYLPYRUVATE | RHONE POULENC CHIM | 1990-01-25 | — | — | JP | disclosed |
| EP-0215414-A2 | Process for producing L-phenylalanine | Kuraray Co., Ltd. (JP) | 1987-03-25 | — | — | EP | disclosed |
| US-4576809-A | COBALT/II/COMPOUND, CARBON MONOXIDE, HYDROXIDE, SULFUR COMPOUND | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1986-03-18 | — | — | US | disclosed |