Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.36 |
| ▸ | FLT1 | P17948 | 12/20 | 0.36 |
| ▸ | FLT4 | P35916 | 12/20 | 0.36 |
| ▸ | KDR | P35968 | 12/20 | 0.36 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683906 | 0.91 | KDR (0.36) | MCHR1FLT1FLT4KDRMCHR2 | |
| SCHEMBL4233974 | 0.87 | SMN1; SMN2 (0.44) | MCHR1KDRMCHR2HTR4SMN1; SMN2 | |
| SCHEMBL4242226 | 0.86 | SMN1; SMN2 (0.43) | MCHR1FLT1FLT4KDRSMN1; SMN2 | |
| SCHEMBL4236569 | 0.85 | MCHR1 (0.46) | MCHR1KDRMCHR2HTR4SMN1; SMN2 | |
| SCHEMBL4228587 | 0.85 | PKM (0.40) | FLT1FLT4KDRHTR4 | |
| SCHEMBL4234061 | 0.84 | SMN1; SMN2 (0.44) | MCHR1MCHR2HTR4SMN1; SMN2NPSR1 | |
| SCHEMBL4240272 | 0.83 | LMNA (0.42) | MCHR1FLT1FLT4KDRHTR4 | |
| SCHEMBL4232415 | 0.83 | HTR4 (0.43) | MCHR1FLT1FLT4KDRHTR4 | |
| SCHEMBL4686817 | 0.83 | KDR (0.40) | MCHR1FLT1FLT4KDRSMN1; SMN2 | |
| SCHEMBL4236062 | 0.82 | MCHR1 (0.47) | MCHR1KDRMCHR2HTR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |