Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682354 | 0.98 | CA2 (0.44) | GRM2CA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4684945 | 0.98 | CA2 (0.44) | GRM2CA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4687467 | 0.95 | ALDH1A1 (0.43) | GRM2CA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4684826 | 0.87 | MAPK1 (0.47) | GRM2CA2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4684282 | 0.82 | GRM2 (0.44) | GRM2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8429843 | 0.82 | GRM2 (0.41) | GRM2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8616038 | 0.82 | GRM2 (0.44) | GRM2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8427404 | 0.81 | GRM2 (0.40) | GRM2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4682349 | 0.81 | GRM2 (0.43) | GRM2ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4684941 | 0.81 | GRM2 (0.43) | GRM2ALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |