Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684979 | 0.85 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL24810085 | 0.84 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL24351930 | 0.76 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL19919837 | 0.71 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL7299085 | 0.69 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL4685229 | 0.69 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL20368086 | 0.68 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL7355004 | 0.68 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT | |
| SCHEMBL7360834 | 0.68 | TXNRD1 (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL7288485 | 0.68 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |