Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | TXN | P10599 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7360840 | 0.85 | TXNRD1 (0.35) | TXNRD1TAAR1TXNALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4005242 | 0.79 | TXNRD1 (0.33) | TXNRD1TAAR1TXNALDH1A1SMN1; SMN2 | |
| SCHEMBL4686081 | 0.77 | ALDH1A1 (0.34) | TXNRD1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2010779 | 0.77 | ALDH1A1 (0.39) | TXNRD1TAAR1TXNALDH1A1SMN1; SMN2 | |
| SCHEMBL11071751 | 0.76 | TXNRD1 (0.38) | TXNRD1TXNALDH1A1SMN1; SMN2 | |
| SCHEMBL4682203 | 0.74 | TAAR1 (0.33) | TXNRD1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4684150 | 0.74 | TXNRD1 (0.33) | TXNRD1TAAR1TXNALDH1A1SMN1; SMN2 | |
| SCHEMBL7349112 | 0.73 | KMT2A (0.33) | ALDH1A1 | |
| SCHEMBL4684154 | 0.72 | FDPS (0.36) | TXNRD1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4686083 | 0.72 | TBXAS1 (0.36) | TXNRD1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |