SCHEMBL4685077

SCHEMBL4685077

CC(C)(C)[Si](C)(C)OCc1cocc1CO[Si](C)(C)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.37
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
DUT P33316 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4685089 0.91 BACE1 (0.36) BACE1MAPTHPGD
SCHEMBL4680026 0.86 BACE1 (0.34) BACE1
SCHEMBL4680030 0.83 ESR1 (0.36) BACE1MAPTHPGD
SCHEMBL3978083 0.80 BACE1 (0.38) BACE1
SCHEMBL4684815 0.79 ESR1 (0.33) BACE1
SCHEMBL14485977 0.77 BACE1 (0.32) BACE1
SCHEMBL23532502 0.77
SCHEMBL8435463 0.72 CETP (0.38) BACE1DUT
SCHEMBL15389825 0.72 BACE1 (0.42) BACE1DUT
SCHEMBL18300443 0.71 USP14 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1362856-B1 WATER-SOLUBLE TRIAZOLE FUNGICIDE DAIICHI SANKYO CO LTD (JP) 2008-09-10 EP disclosed
US-7230023-B2 Water-soluble triazole fungicide SANKYO COMPANY, LIMITED (JP) 2007-06-12 US disclosed
US-20040198790-A1 Water-soluble triazole fungicide SANKYO COMPANY, LIMITED (JP) 2004-10-07 US disclosed
EP-1362856-A1 WATER-SOLUBLE TRIAZOLE FUNGICIDE Sankyo Company, Limited (JP) 2003-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040198790-A1 Water-soluble triazole fungicide ERG28, CYP51A1, XDH BACE1 3297/4885MAPT 2802/4885HPGD 2083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.