Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5149841 | 0.92 | EPHX1 (0.50) | EPHX1EPHX2PTPN1HDAC1HDAC2 | |
| SCHEMBL4686066 | 0.90 | HDAC1 (0.49) | EPHX1EPHX2PTPN2PTPN1HDAC1 | |
| SCHEMBL4686271 | 0.90 | EPHX1 (0.50) | EPHX1EPHX2PTPN2PTPN1ALDH1A1 | |
| SCHEMBL5149417 | 0.89 | EPHX1 (0.52) | EPHX1EPHX2HDAC1HDAC2ALDH1A1 | |
| SCHEMBL5148205 | 0.89 | EPHX1 (0.47) | EPHX1EPHX2PTPN2PTPN1ALDH1A1 | |
| SCHEMBL4785993 | 0.86 | EPHX1 (0.53) | EPHX1EPHX2HDAC1HDAC2ALDH1A1 | |
| SCHEMBL4787348 | 0.86 | EPHX2 (0.55) | EPHX1EPHX2HDAC1HDAC2ALDH1A1 | |
| SCHEMBL4783970 | 0.85 | EPHX2 (0.60) | EPHX1EPHX2ALDH1A1HTTPNLIP | |
| SCHEMBL4786912 | 0.85 | KDR (0.54) | EPHX1EPHX2ALDH1A1HTTKDR | |
| SCHEMBL4786099 | 0.85 | EPHX1 (0.52) | EPHX1EPHX2HDAC1HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |