SCHEMBL5148205

SCHEMBL5148205

CCCCCNC(=O)Nc1ccc(Oc2ccc(N)cc2)c(C(=O)NCCOC)c1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 9/20 0.47
HTR2A P28223 1/20 0.45
EPHX2 P34913 3/20 0.45
KDR P35968 1/20 0.44
PNLIP P16233 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 1/20 0.42
PTPN2 P17706 1/20 0.42
PTPN1 P18031 1/20 0.42
PTPN6 P29350 1/20 0.42
MCHR1 Q99705 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5149841 0.91 EPHX1 (0.50) EPHX1HTR2AEPHX2KDRPNLIP
SCHEMBL5151855 0.90 EPHX1 (0.47) EPHX1EPHX2KDRALDH1A1HTT
SCHEMBL4685589 0.89 EPHX1 (0.50) EPHX1EPHX2KDRPNLIPALDH1A1
SCHEMBL5149417 0.87 EPHX1 (0.52) EPHX1EPHX2KDRPNLIPALDH1A1
SCHEMBL5148190 0.85 PKM (0.48) HTR2APNLIPPTPN2PTPN1PTPN6
SCHEMBL4786912 0.85 KDR (0.54) EPHX1EPHX2KDRALDH1A1HTT
SCHEMBL4786099 0.85 EPHX1 (0.52) EPHX1EPHX2KDRALDH1A1HTT
SCHEMBL4783961 0.84 EPHX1 (0.49) EPHX1EPHX2KDRALDH1A1HTT
SCHEMBL4785993 0.83 EPHX1 (0.53) EPHX1EPHX2KDRALDH1A1HTT
SCHEMBL4787348 0.83 EPHX2 (0.55) EPHX1EPHX2KDRALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007071840-A2 COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF CEREP (FR) 2007-06-28 WO disclosed