Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4685589 | 0.90 | EPHX1 (0.50) | EPHX1ALDH1A1HTTEPHX2PTPN2 | |
| SCHEMBL5151855 | 0.89 | EPHX1 (0.47) | EPHX1ALDH1A1HTTEPHX2KDR | |
| SCHEMBL4686066 | 0.88 | HDAC1 (0.49) | EPHX1ALDH1A1HTTEPHX2PTPN2 | |
| SCHEMBL5150229 | 0.87 | EPHX1 (0.49) | EPHX1ALDH1A1HTTEPHX2KDR | |
| SCHEMBL5149857 | 0.85 | KDR (0.56) | EPHX1ALDH1A1HTTEPHX2KDR | |
| SCHEMBL4683716 | 0.85 | KDR (0.56) | EPHX1ALDH1A1HTTEPHX2KDR | |
| SCHEMBL4687749 | 0.82 | EPHX1 (0.49) | EPHX1ALDH1A1HTTEPHX2KDR | |
| SCHEMBL4682559 | 0.82 | SLC6A3 (0.51) | EPHX1ALDH1A1HTTEPHX2KDR | |
| SCHEMBL4686268 | 0.82 | PKM (0.53) | ALDH1A1PTPN2PTPN1PNLIPKMT2A | |
| SCHEMBL5149841 | 0.81 | EPHX1 (0.50) | EPHX1ALDH1A1HTTEPHX2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |