Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9834517 | 0.77 | — | — | |
| SCHEMBL197102 | 0.76 | — | — | |
| SCHEMBL2928473 | 0.73 | — | — | |
| SCHEMBL9155672 | 0.72 | — | — | |
| SCHEMBL11799848 | 0.72 | — | — | |
| SCHEMBL1444641 | 0.71 | — | — | |
| SCHEMBL114625 | 0.69 | — | — | |
| SCHEMBL28407511 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL138742 | 0.69 | THRB (0.41) | THRB | |
| SCHEMBL9809248 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3376870-A1 | PROCESS FOR THE PREPARATION OF KINASE INHIBITORS AND INTERMEDIATES THEREOF | Aerie Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
| EP-2976080-A1 | COMBINATION THERAPY | Aerie Pharmaceuticals, Inc. (US) | 2016-01-27 | — | — | EP | disclosed |
| WO-2014144781-A1 | COMBINATION THERAPY | AERIE PHARMACEUTICALS, INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| CN-102771479-B | Herbicide composition containing hexazinone and phenoxy carboxylic acid | GAUNGXI TIANYUAN BIOCHEMISTRY | 2014-04-16 | — | — | CN | disclosed |
| CN-102771479-A | Herbicide composition containing hexazinone and phenoxy carboxylic acid | GAUNGXI TIANYUAN BIOCHEMISTRY | 2012-11-14 | — | — | CN | disclosed |
| CN-100485027-C | Method for producing D-lactic acid and spore lactobacillus special for the same | INST OF MICROELECTRONICS CAS (CN) | 2009-05-06 | — | — | CN | disclosed |
| EP-1981847-A1 | SECONDARY AMINES AS RENIN INHIBITORS | Actelion Pharmaceuticals Ltd. (CH) | 2008-10-22 | — | — | EP | disclosed |
| CN-101173240-A | Method for producing D-lactic acid and brood-cell lactobacillus special for the same | CHINESE ACAD INST MICROBIOLOGY (CN) | 2008-05-07 | — | — | CN | disclosed |
| WO-2007088514-A1 | SECONDARY AMINES AS RENIN INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2007-08-09 | — | — | WO | disclosed |