Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686192 | 0.93 | CCR3 (0.41) | CCR3MAPTHSD17B10HPGDTSHR | |
| SCHEMBL4233712 | 0.93 | MAPT (0.38) | CCR3MAPTHSD17B10HPGDTSHR | |
| SCHEMBL4237517 | 0.88 | CCR3 (0.45) | CCR3MAPTHSD17B10HPGDTSHR | |
| SCHEMBL4234129 | 0.88 | MCHR1 (0.42) | CCR3MAPTHSD17B10HPGDTSHR | |
| SCHEMBL4229363 | 0.88 | PKM (0.39) | MAPTHSD17B10TSHRMCHR1KMT2A | |
| SCHEMBL4236062 | 0.82 | MCHR1 (0.47) | MAPTMCHR1KMT2AMEN1EGFR | |
| SCHEMBL4233894 | 0.82 | MCHR1 (0.47) | MAPTMCHR1KMT2AMEN1EGFR | |
| SCHEMBL4242394 | 0.82 | TAS1R3 (0.43) | MAPTHSD17B10TSHRMCHR1KMT2A | |
| SCHEMBL4229610 | 0.81 | CCR3 (0.41) | CCR3MCHR1SSTR5KDRSMN1; SMN2 | |
| SCHEMBL4229397 | 0.81 | MCHR1 (0.44) | MAPTMCHR1KMT2AMEN1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | claimed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | claimed |