Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367948 | 0.91 | GPR84 (0.50) | GPR84PTGS2CYP3A4KMT2AHTR1A | |
| SCHEMBL12097192 | 0.85 | HRH3 (0.44) | GPR84PTGS2CYP3A4HTR1A | |
| SCHEMBL28902375 | 0.80 | HRH3 (0.40) | GPR84PTGS2CYP3A4HTR1A | |
| SCHEMBL1188018 | 0.77 | PTGS2 (0.56) | GPR84PTGS2CYP3A4 | |
| SCHEMBL1188359 | 0.75 | PTGS2 (0.57) | GPR84PTGS2CYP3A4 | |
| SCHEMBL1187372 | 0.75 | PTGS2 (0.57) | GPR84PTGS2CYP3A4 | |
| SCHEMBL1187904 | 0.75 | PTGS2 (0.57) | GPR84PTGS2CYP3A4 | |
| SCHEMBL1186661 | 0.75 | PTGS2 (0.57) | GPR84PTGS2CYP3A4 | |
| SCHEMBL1188092 | 0.75 | PTGS2 (0.57) | GPR84PTGS2CYP3A4 | |
| SCHEMBL1187567 | 0.75 | PTGS2 (0.57) | GPR84PTGS2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |