Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12097192 | 0.94 | HRH3 (0.44) | GPR84PTGS2CYP3A4HTR1A | |
| SCHEMBL4686292 | 0.91 | GPR84 (0.44) | GPR84PTGS2CYP3A4KMT2AHTR1A | |
| SCHEMBL28902375 | 0.88 | HRH3 (0.40) | GPR84PTGS2CYP3A4HTR1A | |
| SCHEMBL3420701 | 0.82 | HRH3 (0.39) | GPR84 | |
| SCHEMBL13103064 | 0.82 | S1PR1 (0.46) | GPR84 | |
| SCHEMBL13103053 | 0.82 | S1PR1 (0.46) | GPR84 | |
| SCHEMBL12097276 | 0.80 | MPO (0.35) | GPR84 | |
| SCHEMBL4562936 | 0.78 | GPR84 (0.49) | GPR84KMT2A | |
| SCHEMBL3411576 | 0.77 | PPARA (0.47) | GPR84PTGS2CYP3A4 | |
| Iodide SCHEMBL3411569 | 0.77 | HRH3 (0.38) | GPR84HTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487870-B1 | Insecticidal and acaricidal diarylpyrrolecarbonitrile and diarylnitropyrrole compounds | AMERICAN CYANAMID CO (US) | 1996-12-18 | — | — | EP | claimed |
| US-8097656-B2 | Nitrogenated trans-stilbene analogs, method for the obtention and medical applications thereof | Dominion Pharmakine S.L (ES) | 2012-01-17 | — | — | US | disclosed |
| US-20110060038-A1 | NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | DOMINION PHARMAKINE S.L. (ES) | 2011-03-10 | — | — | US | disclosed |
| US-20090298905-A1 | Nitrogenatd trans-stilbene analogs, method for the obtention and medical applications thereof | UNIVERSIDAD DEL PAIS VASCO (ES) | 2009-12-03 | — | — | US | disclosed |
| EP-0487111-B1 | A novel color-forming coupler and a silver halide color photographic material containing the same | FUJI PHOTO FILM CO LTD (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5260181-A | Sharpness | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-09 | — | — | US | disclosed |
| EP-0487111-A1 | A novel color-forming coupler and a silver halide color photographic material containing the same | Fuji Photo Film Co., Ltd. (JP) | 1992-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298905-A1 | Nitrogenatd trans-stilbene analogs, method for the obtention and medical applications thereof | TNNI3, TNNT2, INMT | GPR84 1328/4885PTGS2 141/4885CYP3A4 1289/4885 |
| US-20110060038-A1 | NITROGENATED TRANS-STILBENE ANALOGS, METHOD FOR THE OBTENTION AND MEDICAL APPLICATIONS THEREOF | TNNI3, TNNT2, NOS2 | GPR84 1515/4885PTGS2 145/4885CYP3A4 1616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.