Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686343 | 1.00 | GAA (0.46) | GAAKDM4EHRH3CHRNB2CHRNA4 | |
| SCHEMBL4684087 | 0.87 | ALDH1A1 (0.47) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4684093 | 0.87 | ALDH1A1 (0.47) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4741030 | 0.84 | HRH3 (0.48) | GAAKDM4EHRH3ALDH1A1EGFR | |
| SCHEMBL4686742 | 0.82 | HTT (0.56) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4686748 | 0.82 | HTT (0.56) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4688745 | 0.80 | MEN1 (0.47) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4688753 | 0.80 | MEN1 (0.47) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4682865 | 0.79 | MEN1 (0.58) | GAAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL4682855 | 0.79 | MEN1 (0.58) | GAAKDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |