Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684093 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL4686338 | 0.87 | GAA (0.46) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL4686343 | 0.87 | GAA (0.46) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL4686748 | 0.86 | HTT (0.56) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL4686742 | 0.86 | HTT (0.56) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL4683388 | 0.85 | HSPB1 (0.45) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL4683383 | 0.85 | HSPB1 (0.45) | ALDH1A1KMT2AMAPTMEN1HTT | |
| SCHEMBL4688753 | 0.84 | MEN1 (0.47) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL4688745 | 0.84 | MEN1 (0.47) | ALDH1A1KMT2AMAPTMEN1LMNA | |
| SCHEMBL4682865 | 0.83 | MEN1 (0.58) | ALDH1A1KMT2AMAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |