Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PYGM | P11217 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688753 | 1.00 | MEN1 (0.47) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4686742 | 0.88 | HTT (0.56) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4686748 | 0.88 | HTT (0.56) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4682865 | 0.87 | MEN1 (0.58) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4682855 | 0.87 | MEN1 (0.58) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4686948 | 0.85 | MEN1 (0.54) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4686951 | 0.85 | MEN1 (0.54) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4684093 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4684087 | 0.84 | ALDH1A1 (0.47) | MEN1KMT2AMAPTHTTLMNA | |
| SCHEMBL4684500 | 0.83 | HSPB1 (0.50) | MEN1KMT2AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |