Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 6/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | TMPRSS6 | Q8IU80 | 5/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 6/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20487535 | 0.92 | NR1H4 (0.56) | NR1H4F10MEP1BFNTAFNTB | |
| Hydrochloric Acid SCHEMBL7327435 | 0.90 | NR1H4 (0.55) | NR1H4F10MEP1BFNTAFNTB | |
| Trifluoroacetic Acid SCHEMBL17894472 | 0.85 | F10 (0.51) | F2F10TMPRSS6 | |
| Trifluoroacetic Acid SCHEMBL5172108 | 0.84 | HDAC3 (0.52) | F2TMPRSS6KMT2A | |
| Trifluoroacetic Acid SCHEMBL17894369 | 0.83 | ITGB3 (0.55) | NR1H4F2F10NPC1RAB9A | |
| SCHEMBL25295609 | 0.81 | NR1H4 (0.58) | NR1H4MEP1BFNTAFNTBFOLH1 | |
| SCHEMBL30940553 | 0.81 | F10 (0.60) | F2F10MEP1B | |
| SCHEMBL4686388 | 0.81 | F10 (0.46) | NR1H4F2F10TMPRSS6 | |
| SCHEMBL23316731 | 0.79 | NR1H4 (0.58) | NR1H4MEP1BFNTAFNTBFOLH1 | |
| Trifluoroacetic Acid SCHEMBL17894393 | 0.79 | HDAC3 (0.53) | RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1236712-B1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | AJINOMOTO KK (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-6710056-B2 | PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF HAVE AN EXCELLENT ANTAGONISTIC EFFECT AGAINST ACTIVATED BLOOD COAGULATION FACTOR VII. | AJINOMOTO CO., INC. (JP) | 2004-03-23 | — | — | US | disclosed |
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | AJINOMOTO CO. INC (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-1236712-A1 | AMIDINOPHENYLPYRUVIC ACID DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109547-A1 | Amidinophenylpyruvic acid derivatives | HABP2, F2, F7 | NR1H4 1381/4885F2 2/4885F10 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.