Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNLIP | P16233 | 5/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARG | Q86W56 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684136 | 0.83 | PARP10 (0.44) | MAPK14MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4682865 | 0.81 | MEN1 (0.58) | PDE7AMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL4682855 | 0.81 | MEN1 (0.58) | PDE7AMEN1MAPTKMT2ANPSR1 | |
| SCHEMBL4686514 | 0.81 | RAB9A (0.41) | KDRMAPTSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL20577768 | 0.78 | MAPT (0.46) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL4719353 | 0.77 | MEN1 (0.53) | PNLIPMEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4741030 | 0.77 | HRH3 (0.48) | KDR | |
| SCHEMBL13295195 | 0.77 | PDE7A (0.49) | PNLIPSCN9APDE7AMEN1MAPT | |
| SCHEMBL11838457 | 0.76 | KDR (0.51) | PNLIPMAPK14PDE7AKDRMEN1 | |
| SCHEMBL22505690 | 0.76 | MAPT (0.62) | MEN1MAPTKMT2ANPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |