Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5151767 | 0.83 | MAPT (0.50) | PARP10ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4686393 | 0.83 | PNLIP (0.45) | SMN1; SMN2MEN1KMT2AMAPTMAPK14 | |
| SCHEMBL20577768 | 0.82 | MAPT (0.46) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL3561767 | 0.82 | MAPK14 (0.61) | MAPK14BRAF | |
| SCHEMBL14949682 | 0.82 | CDK8 (0.58) | MAPK14 | |
| SCHEMBL4686948 | 0.80 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4686951 | 0.80 | MEN1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4686514 | 0.79 | RAB9A (0.41) | ALDH1A1SMN1; SMN2GAAMAPTTDP1 | |
| SCHEMBL23355301 | 0.78 | NPC1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL4236455 | 0.78 | PKM (0.63) | SMN1; SMN2SLC1A3SLC1A2SLC1A1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |