SCHEMBL46866

SCHEMBL46866

CCCCCCc1cc(CCCCCC)cc(C2(C)c3cc(B4OC(C)(C)C(C)(C)O4)ccc3-c3ccc(B4OC(C)(C)C(C)(C)O4)cc32)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 10/20 0.60
LPL P06858 9/20 0.60
PTGS2 P35354 3/20 0.33
CNR2 P34972 2/20 0.33
TRPA1 O75762 1/20 0.33
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2A6 P11509 1/20 0.33
CYP2B6 P20813 1/20 0.33
CNR1 P21554 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
OPRM1 P35372 1/20 0.33
CYP2J2 P51589 1/20 0.33
CYP1B1 Q16678 1/20 0.33
TRPV1 Q8NER1 1/20 0.33
TRPV3 Q8NET8 1/20 0.33
TRPV4 Q9HBA0 1/20 0.33
TRPV2 Q9Y5S1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18216925 0.94 LIPG (0.54) LIPGLPLCNR2TRPA1CYP1A1
SCHEMBL16302742 0.93 LIPG (0.55) LIPGLPLPTGS2CNR2TRPA1
SCHEMBL9921514 0.91 LIPG (0.60) LIPGLPLPTGS2CNR2TRPA1
SCHEMBL20067408 0.91 LIPG (0.60) LIPGLPLPTGS2CNR2TRPA1
SCHEMBL19001622 0.89 LIPG (0.50) LIPGLPLCNR2TRPA1CYP1A1
SCHEMBL14406681 0.85 LPL (0.54) LIPGLPLPTGS2CNR2TRPA1
SCHEMBL19996226 0.85 LPL (0.54) LIPGLPLPTGS2CNR2TRPA1
SCHEMBL14406716 0.84 LIPG (0.55) LIPGLPLPTGS2CNR2TRPA1
SCHEMBL18001054 0.83 LPL (0.67) LIPGLPLPTGS2SLC6A2HTR2A
SCHEMBL2341239 0.83 LPL (0.67) LIPGLPLPTGS2SLC6A2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10323123-B2 Method of forming polymers CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-06-18 US disclosed
US-10280262-B2 2019-05-07 US disclosed
US-10270037-B2 Polymers, monomers and methods of forming polymers CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2019-04-23 US disclosed
US-20180171076-A1 POLYMER AND DEVICE CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2018-06-21 US disclosed
US-20180097183-A1 POLYMER COMPRISING AN UNSYMMETRIC DIARYLAMINOFLUOREN UNIT SUMIMOTO CHEMICAL COMPANY LIMITED (JP) 2018-04-05 US disclosed
US-9859499-B2 Polymer comprising an unsymmetric diarylaminofluorene unit SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2018-01-02 US disclosed
US-20170145160-A1 METHOD OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-05-25 US disclosed
US-20170145160-A1 METHOD OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-05-25 US disclosed
US-20170098770-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-04-06 US disclosed
US-20170098770-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-04-06 US disclosed
US-20150060798-A1 MONOMERS, POLYMERS AND ORGANIC ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2015-03-05 US disclosed
US-20140353652-A1 POLYMER COMPRISING AN UNSYMMETRIC DIARYLAMINOFLUOREN UNIT CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2014-12-04 US disclosed
US-20140235800-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-08-21 US disclosed
US-20140235800-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2014-08-21 US disclosed
US-20130200348-A1 ORGANIC LIGHT-EMITTING MATERIAL, DEVICE AND METHOD SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-08-08 US disclosed
US-20130200348-A1 ORGANIC LIGHT-EMITTING MATERIAL, DEVICE AND METHOD SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2013-08-08 US disclosed
WO-2013108023-A1 MONOMERS, POLYMERS AND ORGANIC ELECTRONIC DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-07-25 WO disclosed
WO-2013108022-A1 POLYMER COMPRISING AN UNSYMMETRIC DIARYLAMINOFLUOREN UNIT CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-07-25 WO disclosed
WO-2013005026-A2 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-01-10 WO disclosed
WO-2011161417-A1 ORGANIC LIGHT-EMITTING MATERIAL DEVICE AND METHOD CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2011-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170098770-A1 POLYMERS, MONOMERS AND METHODS OF FORMING POLYMERS PCNA, PARG, PARN LIPG 4778/4885LPL 4754/4885PTGS2 1022/4885
US-10270037-B2 Polymers, monomers and methods of forming polymers PCNA, PARG, PARN LIPG 4778/4885LPL 4754/4885PTGS2 1022/4885
US-20180097183-A1 POLYMER COMPRISING AN UNSYMMETRIC DIARYLAMINOFLUOREN UNIT RIF1, CCNA1, TERF2 LIPG 4858/4885LPL 4800/4885PTGS2 2221/4885
US-20140353652-A1 POLYMER COMPRISING AN UNSYMMETRIC DIARYLAMINOFLUOREN UNIT RIF1, CCNA1, RAD1 LIPG 4862/4885LPL 4830/4885PTGS2 2276/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.