Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 4/20 | 0.52 |
| ▸ | BRAF | P15056 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686928 | 0.87 | KMT2A (0.65) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL4686933 | 0.87 | KMT2A (0.65) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL4721618 | 0.82 | KDR (0.55) | KMT2AMEN1KDRBRAFALDH1A1 | |
| SCHEMBL29083270 | 0.82 | KDR (0.57) | KDRBRAF | |
| SCHEMBL4230036 | 0.79 | KMT2A (0.71) | KMT2AMEN1POLBBRAFNAMPT | |
| SCHEMBL4227907 | 0.78 | MEN1 (0.55) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL4786650 | 0.77 | TBXA2R (0.61) | KMT2AMEN1MAPT | |
| SCHEMBL4683934 | 0.76 | KMT2A (0.62) | KMT2AMEN1POLBKDRALDH1A1 | |
| SCHEMBL4683941 | 0.76 | KMT2A (0.62) | KMT2AMEN1POLBKDRALDH1A1 | |
| SCHEMBL3507545 | 0.75 | ALDH1A1 (0.53) | KMT2AMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101370812-A | Fused heterocyclic compound | TAKEDA PHARMACEUTICAL (JP) | 2009-02-18 | — | — | CN | disclosed |
| EP-1957495-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007064045-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |