Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4228422 | 0.85 | ACACB (0.48) | ACACBMMP13MMP14KDM4ENPC1 | |
| SCHEMBL19610351 | 0.83 | FAAH (0.52) | ACACBS1PR5MMP13MMP14KDM4E | |
| SCHEMBL4785267 | 0.83 | EPHX2 (0.48) | MAPTHRH3 | |
| SCHEMBL12509353 | 0.80 | FAAH (0.67) | MAPTALDH1A1 | |
| SCHEMBL20455786 | 0.79 | MAOB (0.61) | NPC1RAB9ANR4A1NR4A2NR4A3 | |
| SCHEMBL19610193 | 0.79 | SMN1; SMN2 (0.53) | ACACBKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL28285822 | 0.77 | ACACB (0.49) | ACACBS1PR5MMP13MMP14KDM4E | |
| SCHEMBL21051312 | 0.76 | MAOB (0.58) | KDM4ENPC1RAB9ANR4A1NR4A2 | |
| SCHEMBL76105 | 0.76 | YAP1 (0.60) | — | |
| SCHEMBL12509224 | 0.76 | MAPT (0.53) | ACACBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |