Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.52 |
| ▸ | DRD3 | P35462 | 4/20 | 0.52 |
| ▸ | HTR7 | P34969 | 6/20 | 0.51 |
| ▸ | DRD5 | P21918 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4689618 | 0.92 | SIGMAR1 (0.53) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| SCHEMBL4684342 | 0.90 | SIGMAR1 (0.54) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| SCHEMBL4684360 | 0.90 | HTR7 (0.53) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| SCHEMBL14079327 | 0.89 | MAPT (0.54) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| SCHEMBL4689638 | 0.89 | HTR7 (0.51) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| SCHEMBL4687021 | 0.89 | DRD2 (0.63) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| SCHEMBL4688657 | 0.88 | HTR7 (0.55) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| SCHEMBL4684376 | 0.88 | DRD2 (0.55) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| Hydrochloric Acid SCHEMBL4685542 | 0.88 | DRD2 (0.62) | SIGMAR1DRD2DRD3HTR7DRD5 | |
| SCHEMBL4684447 | 0.88 | DRD2 (0.54) | SIGMAR1DRD2DRD3HTR7DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828125-B1 | ARYLPIPERAZINE DERIVATIVES AND THEIR USE AS LIGANGS SELECTIVE OF THE DOPAMINE D3 RECEPTOR | BIOPROJET SOC CIV (FR) | 2008-04-09 | — | — | EP | disclosed |