Glycerin

Glycerin

SCHEMBL468813

O=P([O-])([O-])[O-].O=P([O-])([O-])[O-].OCC(O)CO.[Ca+2].[Ca+2].[Ca+2]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.56
ALDH1A1 P00352 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.38
THRB P10828 1/20 0.38
USP2 O75604 1/20 0.32
CYP3A4 P08684 1/20 0.32
SLC34A1 Q06495 1/20 0.32
OR51E2 Q9H255 1/20 0.30
TP53 P04637 1/20 0.30
AKR1B1 P15121 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycerin SCHEMBL15463836 1.00 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL5690684 1.00 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL5903143 0.94 LMNA (0.50) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL1792710 0.94 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL6662558 0.94 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL28918498 0.94 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL1134753 0.94 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL2487171 0.94 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL5161896 0.94 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2
Glycerin SCHEMBL468638 0.94 LMNA (0.56) LMNAALDH1A1SMN1; SMN2THRBUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4432862-A1 ORAL PRODUCTS WITH NICOTINE-POLYMER COMPLEX Nicoventures Trading Limited (GB) 2024-09-25 EP claimed
EP-4188338-A1 BILAYER TABLET COMPRISING EZETIMIBE AND ATORVASTATIN KRKA, d.d., Novo mesto (SI) 2023-06-07 EP claimed
WO-2023084498-A1 ORAL PRODUCTS WITH NICOTINE-POLYMER COMPLEX Nicoventures Trading Limited (GB) 2023-05-19 WO claimed
US-20230148652-A1 ORAL PRODUCTS WITH NICOTINE-POLYMER COMPLEX NICOVENTURES TRADING LTD (GB) 2023-05-18 US claimed
WO-2022023206-A1 BILAYER TABLET COMPRISING EZETIMIBE AND ATORVASTATIN KRKA, D.D., NOVO MESTO (SI) 2022-02-03 WO claimed
WO-2020139237-A2 A BILAYER TABLET FORMULATION OF ATORVASTATIN CALCIUM AND EZETIMIBE SANOVEL ILAC SANAYI VE TICARET ANONIM SIRKETI (TR) 2020-07-02 WO claimed
CN-109688841-A The preparation method of alimentation composition 雀巢产品技术援助有限公司 2019-04-26 CN claimed
US-20180311298-A1 Composition, and Method of Using the Composition, Effective for Minimizing the Harmful Effects Associated With Individuals Suffering from Alcohol Intoxication BURN-OFF, LLC 2018-11-01 US claimed
CN-108516988-A A kind of new technique for synthesizing of toothpaste additive calcium glycerophosphate 扬州工业职业技术学院 2018-09-11 CN claimed
WO-2018146302-A1 PHARMACEUTICAL BILAYER TABLET COMPOSITION OF ATORVASTATIN CALCIUM AND EZETIMIBE SANOVEL ILAC SANAYI VE TICARET A.S. (TR) 2018-08-16 WO claimed
US-20060275223-A1 Erythritol compositions for teeth and gums XLEAR, INC. 2006-12-07 US claimed
EP-1233677-B1 SLOW MELTING COATING FOR ICE CONFECTIONS NESTLE SA (CH) 2005-06-08 EP claimed
WO-2004098294-A1 DOUGH ADDITIVE BRECHET & RICHTER COMPANY (US) 2004-11-18 WO claimed
EP-1171085-B1 ORAL CARE COMPOSITION UNILEVER NV (NL) 2004-08-18 EP claimed
EP-1125575-B1 PERFUSATE PREPARATION FOR OPHTHALMIC OPERATION OPHTECS CORP (JP) 2004-03-03 EP claimed
US-20030180414-A1 Method of controlling release of bitterness inhibitors in chewing gum and gum produced thereby WM. WRIGLEY JR. COMPANY 2003-09-25 US claimed
EP-1123081-B1 HARDENABLE CERAMIC HYDRAULIC CEMENT SYNTHES AG (CH) 2002-12-11 EP claimed
EP-1051086-B1 DIETETIC COMPOSITION IN THE FORM OF A SUBSTITUTION SALT FOR TABLE SALT SANOFI SYNTHELABO (FR) 2002-04-17 EP claimed
EP-0681833-B1 Nasally administrable compositions DOTT RES LAB (JP) 2001-06-13 EP claimed
EP-0719148-B1 ORAL WATER SOLUBLE PHARMACEUTICAL COMPOSITIONS CONTAINING ESTRONE DERIVATIVE AND CALCIUM SALT DEGHENGHI ROMANO (CH) 1998-02-18 EP claimed