Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 3/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047914 | 0.82 | S1PR1 (0.34) | AQP1 | |
| SCHEMBL4596881 | 0.81 | NOTUM (0.36) | NOTUMMAPK14 | |
| SCHEMBL4764345 | 0.75 | AQP1 (0.56) | AQP1NOTUMMAPK14 | |
| SCHEMBL4764341 | 0.74 | AQP1 (0.55) | AQP1NOTUMMAPK14 | |
| SCHEMBL4226033 | 0.72 | AQP1 (0.80) | AQP1NOTUMMAPK14 | |
| SCHEMBL4229976 | 0.72 | AQP1 (0.62) | AQP1NOTUM | |
| SCHEMBL5605280 | 0.72 | AQP1 (0.58) | AQP1NOTUM | |
| SCHEMBL4229969 | 0.72 | AQP1 (0.62) | AQP1NOTUM | |
| SCHEMBL14113467 | 0.72 | AQP1 (0.80) | AQP1NOTUMMAPK14 | |
| SCHEMBL28760844 | 0.70 | AQP1 (0.60) | AQP1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2007030150-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH (US) | 2007-03-15 | — | — | WO | disclosed |