Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MTR | Q99707 | 1/20 | 0.32 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688285 | 0.89 | L3MBTL1 (0.36) | MCHR1L3MBTL1HTR4CARM1PRMT6 | |
| SCHEMBL4693190 | 0.87 | L3MBTL1 (0.39) | MCHR1L3MBTL1ADRA1ADRD3MAPK14 | |
| SCHEMBL4690432 | 0.86 | MCHR1 (0.39) | MCHR1L3MBTL1MAPK14CARM1PRMT6 | |
| SCHEMBL4687554 | 0.85 | L3MBTL1 (0.38) | MCHR1L3MBTL1CARM1PRMT6ALDH1A1 | |
| SCHEMBL4691461 | 0.84 | MCHR1 (0.38) | MCHR1L3MBTL1ADRA1AMAPK14ALDH1A1 | |
| SCHEMBL4690036 | 0.84 | MCHR1 (0.36) | MCHR1L3MBTL1ALDH1A1CNR1 | |
| SCHEMBL1848745 | 0.84 | ALDH1A1 (0.41) | MCHR1L3MBTL1MTTPCHRM2ADRA2A | |
| SCHEMBL5107097 | 0.84 | L3MBTL1 (0.36) | MCHR1L3MBTL1MTTPCHRM2ADRA2A | |
| SCHEMBL4687466 | 0.82 | L3MBTL1 (0.34) | MCHR1L3MBTL1MTTPCHRM2ADRA2A | |
| SCHEMBL4687344 | 0.82 | MCHR1 (0.34) | MCHR1L3MBTL1MAPK14ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443046-B1 | NOVEL 4-(2FUROYL)AMINOPIPERIDINES, INTERMEDIATES IN SYNTHESIZING THE SAME, PROCESS FOR PRODUCING THE SAME AND MEDICINAL USE OF THE SAME | KYORIN SEIYAKU KK (JP) | 2008-12-17 | — | — | EP | disclosed |