Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688703 | 0.84 | MEN1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL4237116 | 0.80 | MEN1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL4236537 | 0.76 | MAPT (0.44) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4231972 | 0.75 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL4226767 | 0.75 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL4235504 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL4233730 | 0.74 | KCNH2 (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2AKCNH2 | |
| SCHEMBL4236267 | 0.73 | KCNH2 (0.36) | ALDH1A1MEN1KMT2AKCNH2 | |
| SCHEMBL4229257 | 0.68 | TTR (0.69) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4683665 | 0.66 | MEN1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |