Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231972 | 0.92 | ALDH1A1 (0.40) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL4226767 | 0.87 | ALDH1A1 (0.36) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL4688699 | 0.84 | MMP13 (0.42) | MEN1KMT2AALDH1A1MAPTKCNH2 | |
| SCHEMBL4238819 | 0.81 | MEN1 (0.41) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL4235504 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL4232271 | 0.79 | MCHR1 (0.38) | KMT2ATTRMETMCHR1LPAR1 | |
| SCHEMBL4236267 | 0.78 | KCNH2 (0.36) | MEN1KMT2ATTRALDH1A1KCNH2 | |
| SCHEMBL4233730 | 0.78 | KCNH2 (0.36) | MEN1KMT2ATTRALDH1A1MAPT | |
| SCHEMBL4237116 | 0.75 | MEN1 (0.41) | MEN1KMT2AALDH1A1MAPTMET | |
| SCHEMBL4236537 | 0.73 | MAPT (0.44) | MEN1KMT2AALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |