SCHEMBL468889

SCHEMBL468889

CC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 1/20 0.54
FOLH1 Q04609 2/20 0.53
SIRT6 Q8N6T7 1/20 0.46
SIRT1 Q96EB6 1/20 0.46
CPB2 Q96IY4 6/20 0.46
PAOX Q6QHF9 2/20 0.43
GNPAT O15228 2/20 0.42
SLC15A2 Q16348 1/20 0.42
NOD1 Q9Y239 1/20 0.41
F2 P00734 1/20 0.41
GSR P00390 1/20 0.41
ITGB3 P05106 1/20 0.40
ITGA2B P08514 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468887 1.00 SLC6A5 (0.54) SLC6A5FOLH1SIRT6SIRT1CPB2
SCHEMBL29396814 0.88 SIRT6 (0.58) SLC6A5FOLH1SIRT6SIRT1CPB2
SCHEMBL16494900 0.87 SLC6A5 (0.43) SLC6A5FOLH1SIRT6SIRT1CPB2
SCHEMBL30645373 0.86 SLC6A5 (0.56) SLC6A5FOLH1SIRT6SIRT1CPB2
SCHEMBL15756737 0.86 FOLH1 (0.54) SLC6A5FOLH1CPB2GNPATSLC15A2
SCHEMBL4299646 0.86 FOLH1 (0.54) SLC6A5FOLH1CPB2GNPATSLC15A2
SCHEMBL4653470 0.85 FURIN (0.45) SLC6A5SIRT6SIRT1PAOXF2
SCHEMBL20013183 0.85 SIRT6 (0.44) SLC6A5FOLH1SIRT6SIRT1PAOX
SCHEMBL4653469 0.85 FURIN (0.45) SLC6A5SIRT6SIRT1PAOXF2
SCHEMBL8821210 0.84 FOLH1 (0.53) SLC6A5FOLH1CPB2GNPATSLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119506210-A Primary taste bud cell sensitive to salty taste enhancing peptide and preparation method and application thereof 上海应用技术大学 2025-02-25 CN disclosed
EP-2311452-B2 Topical composition comprising n-acetyl glucosamine YU RUEY J (US) 2020-12-30 EP disclosed
EP-2311452-B9 Topical composition comprising n-acetyl glucosamine YU RUEY J (US) 2014-12-24 EP disclosed
US-RE44302-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-06-18 US disclosed
US-RE44017-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-02-19 US disclosed
US-RE42902-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2011-11-08 US disclosed
EP-2311452-A1 Topical composition comprising n-acetyl glucosamine Yu, Ruey J. (US) 2011-04-20 EP disclosed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 US disclosed
US-RE41278-E1 N-acetyl aldosamines and related N-acetyl compounds, and their topical use TRISTRATA, INC. 2010-04-27 US disclosed
EP-2080504-A2 Topical composition comprising n-acetylaldosamines or n-acetylamino acids Yu, Ruey J. (US) 2009-07-22 EP disclosed
US-6380192-B1 FOR INHIBITING NONENZYMATIC CROSS-LINKING (PROTEIN AGING) ALTEON, INC. 2002-04-30 US disclosed
EP-1143925-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2001-10-17 EP disclosed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US disclosed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO disclosed
US-6060470-A Triazine compounds and methods of use therefor ALTEON, INC. 2000-05-09 US disclosed
US-5932578-A CAPABLE OF INHIBITING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS OF TARGET PROTEINS. FOOD SPOILAGE AND ANIMAL PROTEIN AGING CAN BE TREATED. ALTEON INC. (US) 1999-08-03 US disclosed
US-5877217-A INHIBITING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS OF TARGET PROTEINS. INHIBITING THE DISCOLORATION OF TEETH. ALTEON INC. (US) 1999-03-02 US disclosed
US-5661139-A FOR INHIBITING GLYCOSYLATION OF PROTEINS TO PREVENT DISCOLORATION OF THE TEETH ALTEON INC. (US) 1997-08-26 US disclosed
US-4564596-A Urokinase derivatives covalently bound to fibrinogen VSESOJUZNY KARDIOLOGICHESKY NAUCHNY TSENTR AKADEMII MEDITSINSKIKH NAUK SSSR, USSR, MOSCOW, 3 CHEREPKOVSKAYA ULITSA, 15A 1986-01-14 US disclosed
US-3950223-A WATER SOLUBLE AMINO SUGARS, AMINO ACIDS, AND CATIONIC SURFACTANTS AJINOMOTO CO., INC. (JA) 1976-04-13 US disclosed